Ontology highlight
ABSTRACT:
SUBMITTER: Ruers T
PROVIDER: S-EPMC3457746 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Ruers T T Punt C C Van Coevorden F F Pierie J P E N JPEN Borel-Rinkes I I Ledermann J A JA Poston G G Bechstein W W Lentz M A MA Mauer M M Van Cutsem E E Lutz M P MP Nordlinger B B
Annals of oncology : official journal of the European Society for Medical Oncology 20120319 10
<h4>Background</h4>This study investigates the possible benefits of radiofrequency ablation (RFA) in patients with non-resectable colorectal liver metastases.<h4>Methods</h4>This phase II study, originally started as a phase III design, randomly assigned 119 patients with non-resectable colorectal liver metastases between systemic treatment (n = 59) or systemic treatment plus RFA ( ± resection) (n = 60). Primary objective was a 30-month overall survival (OS) rate >38% for the combined treatment ...[more]