Ontology highlight
ABSTRACT:
SUBMITTER: Bender HS
PROVIDER: S-EPMC3458001 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Bender Hannah S HS Murchison Elizabeth P EP Pickett Hilda A HA Deakin Janine E JE Strong Margaret A MA Conlan Carly C McMillan Daniel A DA Neumann Axel A AA Greider Carol W CW Hannon Gregory J GJ Reddel Roger R RR Graves Jennifer A Marshall JA
PloS one 20120925 9
Telomeres, specialised structures that protect chromosome ends, play a critical role in preserving chromosome integrity. Telomere dynamics in the Tasmanian devil (Sarcophilus harrisii) are of particular interest in light of the emergence of devil facial tumour disease (DFTD), a transmissible malignancy that causes rapid mortality and threatens the species with extinction. We used fluorescent in situ hybridisation to investigate telomere length in DFTD cells, in healthy Tasmanian devils and in fo ...[more]