Ontology highlight
ABSTRACT:
SUBMITTER: Dharap A
PROVIDER: S-EPMC3458128 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Dharap Ashutosh A Nakka Venkata Prasuja VP Vemuganti Raghu R
Stroke 20120904 10
<h4>Background and purpose</h4>Long noncoding RNAs (lncRNAs) play a significant role in cellular physiology. We evaluated the effect of focal ischemia on the expression of 8314 lncRNAs in rat cerebral cortex using microarrays.<h4>Methods</h4>Ischemia was induced by transient middle cerebral artery occlusion. Genomic and transcriptomic correlates of the stroke-responsive lncRNAs and the transcription factor binding sties in their promoters were evaluated with bioinformatics.<h4>Results</h4>Three ...[more]