Saccadic eye movements evoked by optogenetic activation of primate V1.
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ABSTRACT:
SUBMITTER: Jazayeri M
PROVIDER: S-EPMC3458167 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
Saccadic eye movements evoked by optogenetic activation of primate V1.
Jazayeri Mehrdad M Lindbloom-Brown Zachary Z Horwitz Gregory D GD
Nature neuroscience 20120902 10
Optogenetics has advanced our understanding of the neural basis of simple behaviors in rodents and small animals. In primates, however, for which more sophisticated behavioral assays exist, optogenetic manipulations of behavior have been unsuccessful. We found that monkeys reliably shifted their gaze toward the receptive field of optically driven channelrhodopsin-2-expressing neurons of the primary visual cortex. This result establishes optogenetics as a viable tool for the causal analysis of be ...[more]
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