Structural architecture and functional evolution of Wnts.
Ontology highlight
ABSTRACT:
SUBMITTER: Bazan JF
PROVIDER: S-EPMC3458506 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Publications
Structural architecture and functional evolution of Wnts.
Bazan J Fernando JF Janda Claudia Y CY Garcia K Christopher KC
Developmental cell 20120801 2
The crystal structure of a Wnt morphogen bound to its Frizzled receptor ectodomain provides insights into the evolutionary provenance of this complex fold and offers an explanation for why Wnts utilize both lipid- and protein-mediated contacts to engage Frizzleds. ...[more]
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