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Screening of ligands for the Ullmann synthesis of electron-rich diaryl ethers.

ABSTRACT: In the search for new ligands for the Ullmann diaryl ether synthesis, permitting the coupling of electron-rich aryl bromides at relatively low temperatures, 56 structurally diverse multidentate ligands were screened in a model system that uses copper iodide in acetonitrile with potassium phosphate as the base. The ligands differed largely in their performance, but no privileged structural class could be identified.

SUBMITTER: Otto N

PROVIDER: S-EPMC3458727 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Screening of ligands for the Ullmann synthesis of electron-rich diaryl ethers.

Otto Nicola N Opatz Till T

Beilstein journal of organic chemistry 20120717

In the search for new ligands for the Ullmann diaryl ether synthesis, permitting the coupling of electron-rich aryl bromides at relatively low temperatures, 56 structurally diverse multidentate ligands were screened in a model system that uses copper iodide in acetonitrile with potassium phosphate as the base. The ligands differed largely in their performance, but no privileged structural class could be identified. ...[more]

PMID: 23019437

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