Ontology highlight
ABSTRACT:
SUBMITTER: Naesens M
PROVIDER: S-EPMC3459071 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Naesens M M Salvatierra O O Benfield M M Ettenger R B RB Dharnidharka V V Harmon W W Mathias R R Sarwal M M MM
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120613 10
Steroid avoidance is safe and effective in children receiving kidney transplants in terms of graft function and survival, but the effects on allograft histology are unknown. In this multicenter trial, 130 pediatric renal transplant recipients were randomized to steroid-free (SF; n = 60) or steroid-based (SB; n = 70) immunosuppression, and underwent renal allograft biopsies at the time of graft dysfunction and per protocol at implantation and 6, 12 and 24 months after transplantation. Clinical fo ...[more]