Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC3459215 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Zhang Xuemei X Lin Jie J Wu Xifeng X Lin Zhongning Z Ning Baitang B Kadlubar Susan S Kadlubar Fred F FF
International journal of molecular epidemiology and genetics 20120831 3
This study sought to determine the role of copy number variants (CNV) combined with other genetic variants in the Glutathione S-transferases Mu class1 (GSTM1) promoter in the development of urinary bladder cancer. TaqMan real-time PCR and direct sequencing were used to determine genetic variants. Haploblocks and haplotype were constructed and estimated by Haploview and Phase, respectively. Logistic regression revealed a significantly decreased bladder cancer risk in subjects with at least 2 copi ...[more]