Biomodulatory approaches to photodynamic therapy for solid tumors.
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ABSTRACT:
SUBMITTER: Anand S
PROVIDER: S-EPMC3459352 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Publications
Biomodulatory approaches to photodynamic therapy for solid tumors.
Anand Sanjay S Ortel Bernhard J BJ Pereira Stephen P SP Hasan Tayyaba T Maytin Edward V EV
Cancer letters 20120725 1
Photodynamic Therapy (PDT) uses a photosensitizing drug in combination with visible light to kill cancer cells. PDT has an advantage over surgery or ionizing radiation because PDT can eliminate tumors without causing fibrosis or scarring. Disadvantages include the dual need for drug and light, and a generally lower efficacy for PDT vs. surgery. This minireview describes basic principles of PDT, photosensitizers available, and aspects of tumor biology that may provide further opportunities for tr ...[more]
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