Ontology highlight
ABSTRACT:
SUBMITTER: Chuang HY
PROVIDER: S-EPMC3460686 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Chuang Han-Yu HY Rassenti Laura L Salcedo Michelle M Licon Kate K Kohlmann Alexander A Haferlach Torsten T Foà Robin R Ideker Trey T Kipps Thomas J TJ
Blood 20120726 13
The clinical course of patients with chronic lymphocytic leukemia (CLL) is heterogeneous. Several prognostic factors have been identified that can stratify patients into groups that differ in their relative tendency for disease progression and/or survival. Here, we pursued a subnetwork-based analysis of gene expression profiles to discriminate between groups of patients with disparate risks for CLL progression. From an initial cohort of 130 patients, we identified 38 prognostic subnetworks that ...[more]