Ontology highlight
ABSTRACT:
SUBMITTER: Fagermoen E
PROVIDER: S-EPMC3461473 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Fagermoen Even E Sulheim Dag D Winger Anette A Andersen Anders M AM Vethe Nils Tore NT Saul J Philip JP Thaulow Erik E Wyller Vegard Bruun VB
BMC research notes 20120807
<h4>Background</h4>This pilot study (ClinicalTrials.gov ID: NCT01507701) assessed the feasibility and safety of clonidine in adolescent chronic fatigue syndrome (CFS). Specifically, we assessed clonidine dosage in relation to a) plasma concentration levels, b) orthostatic cardiovascular responses, and c) possible adverse effects.<h4>Findings</h4>Five adolescent CFS patients (14-19 years old) received 50 μg clonidine twice per day during 14 days in an open, uncontrolled design. Plasma concentrati ...[more]