Ontology highlight
ABSTRACT:
SUBMITTER: Lai VK
PROVIDER: S-EPMC3462241 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Lai Victor K VK Frey Christina R CR Kerandi Allan M AM Lake Spencer P SP Tranquillo Robert T RT Barocas Victor H VH
Acta biomaterialia 20120722 11
Collagen and fibrin are important extracellular matrix (ECM) components in the body, providing structural integrity to various tissues. These biopolymers are also common scaffolds used in tissue engineering. This study investigated how co-gelation of collagen and fibrin affected the properties of each individual protein network. Collagen-fibrin co-gels were cast and subsequently digested using either plasmin or collagenase; the microstructure and mechanical behavior of the resulting networks wer ...[more]