Ontology highlight
ABSTRACT:
SUBMITTER: Saar BG
PROVIDER: S-EPMC3462359 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Saar Brian G BG Freudiger Christian W CW Reichman Jay J Stanley C Michael CM Holtom Gary R GR Xie X Sunney XS
Science (New York, N.Y.) 20101201 6009
Optical imaging in vivo with molecular specificity is important in biomedicine because of its high spatial resolution and sensitivity compared with magnetic resonance imaging. Stimulated Raman scattering (SRS) microscopy allows highly sensitive optical imaging based on vibrational spectroscopy without adding toxic or perturbative labels. However, SRS imaging in living animals and humans has not been feasible because light cannot be collected through thick tissues, and motion-blur arises from slo ...[more]