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Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate.


ABSTRACT: The success of nanorobotics requires the precise placement and subsequent operation of specific nanomechanical devices at particular locations. The structural programmability of DNA makes it a particularly attractive system for nanorobotics. We have developed a cassette that enables the placement of a robust, sequence-dependent DNA robot arm within a two-dimensional (2D) crystalline DNA array. The cassette contains the device, an attachment site, and a reporter of state. We used atomic force microscopy to demonstrate that the rotary device is fully functional after insertion. Thus, a nanomechanical device can operate within a fixed frame of reference.

SUBMITTER: Ding B 

PROVIDER: S-EPMC3463378 | biostudies-literature | 2006 Dec

REPOSITORIES: biostudies-literature

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Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate.

Ding Baoquan B   Seeman Nadrian C NC  

Science (New York, N.Y.) 20061201 5805


The success of nanorobotics requires the precise placement and subsequent operation of specific nanomechanical devices at particular locations. The structural programmability of DNA makes it a particularly attractive system for nanorobotics. We have developed a cassette that enables the placement of a robust, sequence-dependent DNA robot arm within a two-dimensional (2D) crystalline DNA array. The cassette contains the device, an attachment site, and a reporter of state. We used atomic force mic  ...[more]

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