Ontology highlight
ABSTRACT:
SUBMITTER: Cameron EA
PROVIDER: S-EPMC3464567 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Cameron Elizabeth A EA Maynard Mallory A MA Smith Christopher J CJ Smith Thomas J TJ Koropatkin Nicole M NM Martens Eric C EC
The Journal of biological chemistry 20120821 41
Human colonic bacteria are necessary for the digestion of many dietary polysaccharides. The intestinal symbiont Bacteroides thetaiotaomicron uses five outer membrane proteins to bind and degrade starch. Here, we report the x-ray crystallographic structures of SusE and SusF, two outer membrane proteins composed of tandem starch specific carbohydrate-binding modules (CBMs) with no enzymatic activity. Examination of the two CBMs in SusE and three CBMs in SusF reveals subtle differences in the way e ...[more]