Ontology highlight
ABSTRACT:
SUBMITTER: Lu H
PROVIDER: S-EPMC3466332 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Organic letters 20120921 19
The cobalt(II) complex of 3,5-Di(t)Bu-IbuPhyrin, [Co(P1)], is an effective catalyst for intramolecular amination of electron-deficient C-H bonds, including those adjacent to electron-withdrawing CO(2)R, C(O)NR(2), C(O)R, and CN groups, in excellent yields with high regio- and stereoselectivity. The [Co(P1)]-catalyzed amination system provides a direct method for the synthesis of α-amino acid derivatives from the corresponding carboxylate precursors. ...[more]