Ontology highlight
ABSTRACT:
SUBMITTER: Grasman J
PROVIDER: S-EPMC3469545 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Grasman Johan J Grasman Raoul P P P RP van der Maas Han L J HL
PloS one 20121011 10
The intake of nicotine by smoking cigarettes is modelled by a dynamical system of differential equations. The variables are the internal level of nicotine and the level of craving. The model is based on the dynamics of neural receptors and the way they enhance craving. Lighting of a cigarette is parametrised by a time-dependent Poisson process. The nicotine intake rate is assumed to be proportional with the parameter of this stochastic process. The effect of craving is damped by a control mechan ...[more]