The influence of gene-environment interactions on the development of alcoholism and drug dependence.
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ABSTRACT:
SUBMITTER: Enoch MA
PROVIDER: S-EPMC3470472 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Publications
The influence of gene-environment interactions on the development of alcoholism and drug dependence.
Current psychiatry reports 20120401 2
Alcoholism and drug dependence are common psychiatric disorders with a heritability of about 50%; therefore genetic and environmental influences are equally important. Early-life stress is a predictor of adolescent problem drinking/drug use and alcohol/drug dependence in adulthood, but moderating factors governing the availability of alcohol/drug are important. The risk-resilience balance for addiction may be due in part to the interaction between genetic variation and environment stressors (G × ...[more]
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