Ontology highlight
ABSTRACT:
SUBMITTER: An S
PROVIDER: S-EPMC34710 | biostudies-literature | 2001 Jun
REPOSITORIES: biostudies-literature
An S S Cutler G G Zhao J J JJ Huang S G SG Tian H H Li W W Liang L L Rich M M Bakleh A A Du J J Chen J L JL Dai K K
Proceedings of the National Academy of Sciences of the United States of America 20010601 13
Melanin-concentrating hormone (MCH), a neuropeptide expressed in central and peripheral nervous systems, plays an important role in the control of feeding behaviors and energy metabolism. An orphan G protein-coupled receptor (SLC-1/GPR24) has recently been identified as a receptor for MCH (MCHR1). We report here the identification and characterization of a G protein-coupled receptor as the MCH receptor subtype 2 (MCHR2). MCHR2 has higher protein sequence homology to MCHR1 than any other G protei ...[more]