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Automated and fast building of three-dimensional RNA structures.


ABSTRACT: Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an automated and fast program, 3dRNA, for RNA tertiary structure prediction with reasonable accuracy for RNAs of larger size and complex topology.

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC3471093 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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Automated and fast building of three-dimensional RNA structures.

Zhao Yunjie Y   Huang Yangyu Y   Gong Zhou Z   Wang Yanjie Y   Man Jianfen J   Xiao Yi Y  

Scientific reports 20121015


Building tertiary structures of non-coding RNA is required to understand their functions and design new molecules. Current algorithms of RNA tertiary structure prediction give satisfactory accuracy only for small size and simple topology and many of them need manual manipulation. Here, we present an automated and fast program, 3dRNA, for RNA tertiary structure prediction with reasonable accuracy for RNAs of larger size and complex topology. ...[more]

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