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The potential benefit of stem cell therapy after stroke: an update.

ABSTRACT: Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explore the challenges to making this a realistic treatment option for the future.

SUBMITTER: Banerjee S 

PROVIDER: S-EPMC3471602 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

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The potential benefit of stem cell therapy after stroke: an update.

Banerjee Soma S   Williamson Deborah A DA   Habib Nagy N   Chataway Jeremy J  

Vascular health and risk management 20121010

Stroke is a leading cause of death and disability worldwide. Stem cell therapy is an emerging therapeutic modality with evidence of significant benefits in preclinical stroke models. A number of phase I and II clinical trials have now been completed, with several more currently under way. Translation to the bedside, however, remains a long way off, and there are many questions that remain unanswered. This review will summarize the current evidence and ongoing clinical trials worldwide, and explo  ...[more]

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