Ontology highlight
ABSTRACT:
SUBMITTER: Jimenez E
PROVIDER: S-EPMC3474832 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Jiménez Elizabeth E Sefah Kwame K López-Colón Dalia D Van Simaeys Dimitri D Chen Hui William HW Tockman Melvyn S MS Tan Weihong W
PloS one 20121017 10
Lung cancer is the most lethal malignancy in the world, and each year thousands of people die from this disease. Early detection has proven to increase the 5-year survival for this cancer in general, independent of the origination site in the lung. To address this challenge, we have used cell-based SELEX (Systematic Evolution of Ligands by Exponential Enrichment) to select a panel of aptamers capable of distinguishing lung adenocarcinoma cells from normal lung epithelial cells. These aptamers bi ...[more]