Ontology highlight
ABSTRACT:
SUBMITTER: Bell E
PROVIDER: S-EPMC3475152 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Bell Emma E Richardson Gavin D GD Jahoda Colin A CA Gledhill Karl K Phillips Helen M HM Henderson Deborah D Owens W Andrew WA Hole Nicholas N
Stem cells and development 20120627 16
In this study, we have demonstrated that cells of neural crest origin located in the dermal papilla (DP) exhibit endothelial marker expression and a functional activity. When grown in endothelial growth media, DP primary cultures upregulate expression of vascular endothelial growth factor receptor 1 (FLT1) mRNA and downregulate expression of the dermal stem cell marker α-smooth muscle actin. DP cells have demonstrated functional characteristics of endothelial cells, including the ability to form ...[more]