Ontology highlight
ABSTRACT:
SUBMITTER: Shortreed SM
PROVIDER: S-EPMC3475611 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Journal of the Royal Statistical Society. Series C, Applied statistics 20120531 4
Treatment of schizophrenia is notoriously difficult and typically requires personalized adaption of treatment due to lack of efficacy of treatment, poor adherence, or intolerable side effects. The Clinical Antipsychotic Trials in Intervention Effectiveness (CATIE) Schizophrenia Study is a sequential multiple assignment randomized trial comparing the typical antipsychotic medication, perphenazine, to several newer atypical antipsychotics. This paper describes the marginal structural modeling meth ...[more]