Ontology highlight
ABSTRACT:
SUBMITTER: McDole K
PROVIDER: S-EPMC3477249 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Genesis (New York, N.Y. : 2000) 20120816 10
To understand cell fate specification and maintenance during development, it is essential to visualize both lineage markers and cell behaviors in real time using endogenous markers to report cell fate. We have generated a reporter line in which eGFP is fused to the endogenous locus of Cdx2, a transcription factor essential for trophectoderm specification, allowing us to visualize cell fate decisions in the preimplantation mouse embryo. We used two-photon laser scanning microscopy to visualize ex ...[more]