Ontology highlight
ABSTRACT:
SUBMITTER: Dudley JT
PROVIDER: S-EPMC3477496 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 20110101
The diagnosis and treatment of cancers, which rank among the leading causes of mortality in developed nations, presents substantial clinical challenges. The genetic and epigenetic heterogeneity of tumors can lead to differential response to therapy and gross disparities in patient outcomes, even for tumors originating from similar tissues. High-throughput DNA sequencing technologies hold promise to improve the diagnosis and treatment of cancers through efficient and economical profiling of compl ...[more]