Ontology highlight
ABSTRACT:
SUBMITTER: Chauhan V
PROVIDER: S-EPMC3477555 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Chauhan Vinita V Howland Matthew M
TheScientificWorldJournal 20121011
This study examined alpha (α-) particle radiation effects on global changes in gene expression in human leukemic monocytic cells (THP-1) for the purposes of mining for candidate biomarkers that could be used for the development of a biological assessment tool. THP-1 cells were exposed to α-particle radiation at a dose range of 0 to 1.5 Gy. Twenty-four hours and three days after exposure gene expression was monitored using microarray technology. A total of 16 genes were dose responsive and classi ...[more]