A suite of citrate-derived siderophores from a marine Vibrio species isolated following the Deepwater Horizon oil spill.

ABSTRACT: Nearly all microbes require iron for growth. The low concentration of iron found in the ocean makes iron acquisition a particularly difficult task. In response to these low iron conditions, many bacteria produce low-molecular-weight iron-binding molecules called siderophores to aid in iron uptake. We report herein the isolation and structural characterization of a suite of amphiphilic siderophores called the ochrobactins-OH, which are produced by a Vibrio species isolated from the Gulf of Mexico after the 2010 Deepwater Horizon oil spill. The citrate-based ochrobactins-OH are derivatives of aerobactin, replacing the acetyl groups with fatty acid appendages ranging in size from C8 to C12, and are distinctly different from the ochrobactins in that the fatty acid appendages are hydroxylated r

SUBMITTER: Gauglitz JM 

PROVIDER: S-EPMC3477609 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature