Ontology highlight
ABSTRACT:
SUBMITTER: Aslankoohi E
PROVIDER: S-EPMC3479212 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Aslankoohi Elham E Voordeckers Karin K Sun Hong H Sanchez-Rodriguez Aminael A van der Zande Elisa E Marchal Kathleen K Verstrepen Kevin J KJ
Nucleic acids research 20120816 19
Genetic transformation is a natural process during which foreign DNA enters a cell and integrates into the genome. Apart from its relevance for horizontal gene transfer in nature, transformation is also the cornerstone of today's recombinant gene technology. Despite its importance, relatively little is known about the factors that determine transformation efficiency. We hypothesize that differences in DNA accessibility associated with nucleosome positioning may affect local transformation effici ...[more]