Ontology highlight
ABSTRACT:
SUBMITTER: Vlahu CA
PROVIDER: S-EPMC3482728 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Vlahu Carmen A CA Lemkes Bregtje A BA Struijk Dirk G DG Koopman Marion G MG Krediet Raymond T RT Vink Hans H
Journal of the American Society of Nephrology : JASN 20121018 11
Damage to the endothelial glycocalyx, which helps maintain vascular homeostasis, heightens the sensitivity of the vasculature to atherogenic stimuli. Patients with renal failure have endothelial dysfunction and increased risk for cardiovascular morbidity and mortality, but the state of the endothelial glycocalyx in these patients is unknown. Here, we used Sidestream Darkfield imaging to detect changes in glycocalyx dimension in dialysis patients and healthy controls from in vivo recordings of th ...[more]