Ontology highlight
ABSTRACT:
SUBMITTER: Kamm CP
PROVIDER: S-EPMC3484273 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Kamm Christian Philipp CP El-Koussy Marwan M Humpert Sebastian S Findling Oliver O von Bredow Ferdinand F Burren Yuliya Y Schwegler Guido G Schött Dagmar D Donati Filippo F Müller Martin M Goebels Norbert N Müller Felix F Slotboom Johannes J Tettenborn Barbara B Kappos Ludwig L Naegelin Yvonne Y Mattle Heinrich Paul HP
Journal of neurology 20120509 11
Statins have anti-inflammatory and immunomodulatory properties in addition to lipid-lowering effects. The present study evaluated the effect of atorvastatin added to interferon beta-1b in multiple sclerosis (MS) in a multicenter, randomized, parallel-group, rater-blinded study performed in eight Swiss hospitals. Seventy-seven patients with relapsing-remitting MS started interferon beta-1b every other day. After 3 months, they were randomized 1:1 to receive atorvastatin 40 mg/day or not in additi ...[more]