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Sexual transmission of predicted CXCR4-tropic HIV-1 likely originating from the source partner's seminal cells.


ABSTRACT: We present a case of sexual transmission of HIV-1 predicted to have CXCR4-tropism during male-to-male sexual exposure. Phylogenetic analyses exclude cell-free virus in the seminal plasma of the source partner and possibly point to the seminal cells as the origin of the transmission event.

SUBMITTER: Gianella S 

PROVIDER: S-EPMC3485073 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Sexual transmission of predicted CXCR4-tropic HIV-1 likely originating from the source partner's seminal cells.

Gianella Sara S   Mehta Sanjay R SR   Young Jason A JA   Vargas Milenka V MV   Little Susan J SJ   Richman Douglas D DD   Kosakovsky Pond Sergei L SL   Smith Davey M DM  

Virology 20121003 1


We present a case of sexual transmission of HIV-1 predicted to have CXCR4-tropism during male-to-male sexual exposure. Phylogenetic analyses exclude cell-free virus in the seminal plasma of the source partner and possibly point to the seminal cells as the origin of the transmission event. ...[more]

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