Ontology highlight
ABSTRACT:
SUBMITTER: Deracinois B
PROVIDER: S-EPMC3485243 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Deracinois Barbara B Duban-Deweer Sophie S Pottiez Gwënaël G Cecchelli Roméo R Karamanos Yannis Y Flahaut Christophe C
PloS one 20121031 10
Although the physiological properties of the blood-brain barrier (BBB) are relatively well known, the phenotype of the component brain capillary endothelial cells (BCECs) has yet to be described in detail. Likewise, the molecular mechanisms that govern the establishment and maintenance of the BBB are largely unknown. Proteomics can be used to assess quantitative changes in protein levels and identify proteins involved in the molecular pathways responsible for cellular differentiation. Using the ...[more]