Unique mitochondrial DNA in highly inbred feral cattle.
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ABSTRACT:
SUBMITTER: Hudson G
PROVIDER: S-EPMC3485552 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
Unique mitochondrial DNA in highly inbred feral cattle.
Hudson Gavin G Wilson Ian I Payne Brendan I A BI Elson Joanna J Samuels David C DC Santibanez-Korev Mauro M Hall Stephen J G SJ Chinnery Patrick F PF
Mitochondrion 20120517 4
The Chillingham herd of wild Northumbrian cattle remains viable despite over 300 years of in-breeding and a near-homozygous nuclear genome. Here we report the complete mitochondrial DNA sequence using ultra-deep next generation sequencing. Random population sampling of ~10% of the extant herd identified a single mtDNA haplotype harbouring a unique bovine variant present in all other higher mammals (m.11789C/Y421H) which may contribute to their survival. ...[more]
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