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Genetic heterogeneity and recombination in human type 2 astroviruses.


ABSTRACT: Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3' end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.

SUBMITTER: De Grazia S 

PROVIDER: S-EPMC3486218 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Genetic heterogeneity and recombination in human type 2 astroviruses.

De Grazia S S   Medici M C MC   Pinto P P   Moschidou P P   Tummolo F F   Calderaro A A   Bonura F F   Banyai K K   Giammanco G M GM   Martella V V  

Journal of clinical microbiology 20120829 11


Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3' end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified. ...[more]

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