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Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States.

ABSTRACT: Two genomes of a new porcine circovirus type 2 (PCV2) strain associated with cases of perceived failure of PCV2 vaccination were sequenced and analyzed. Based on the genome, this is the first report of this mutant of PCV2b in the United States. The genomic knowledge of this mutant PCV2b will improve understanding of the epidemiology of PCV and potentially inform the development of new and more effective vaccines for PCV2.

SUBMITTER: Xiao CT

PROVIDER: S-EPMC3486456 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Complete genome sequence of a novel porcine circovirus type 2b variant present in cases of vaccine failures in the United States.

Xiao Chao-Ting CT Halbur Patrick G PG Opriessnig Tanja T

Journal of virology 20121101 22

Two genomes of a new porcine circovirus type 2 (PCV2) strain associated with cases of perceived failure of PCV2 vaccination were sequenced and analyzed. Based on the genome, this is the first report of this mutant of PCV2b in the United States. The genomic knowledge of this mutant PCV2b will improve understanding of the epidemiology of PCV and potentially inform the development of new and more effective vaccines for PCV2. ...[more]

PMID: 23087125

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