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Complete genome sequence of a Newcastle disease virus strain isolated from broiler breeder flocks in China.


ABSTRACT: In 2010 and 2011, several devastating Newcastle disease (ND) outbreaks occurred in China, affecting broilers, layers, and breeders. The CK-JSX1-201005 virus was isolated from broiler breeder flocks vaccinated with the classical ND virus (NDV) vaccine program, but laying rate decreased from 80% to 30 to 40% in the clinic. Here, we report the complete genome sequence and molecular characteristic of the CK-JSX1-201005 NDV. These findings provide additional insights into the genetic variation of NDV circulating in China and are useful for vaccine development for NDV.

SUBMITTER: Chen F 

PROVIDER: S-EPMC3486497 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Complete genome sequence of a Newcastle disease virus strain isolated from broiler breeder flocks in China.

Chen Feng F   Liu Jiajia J   Liu Di D   Yan Zhuanqiang Z   Ji Jun J   Qin Jianping J   Li Haiyan H   Ma Jingyun J   Bi Yingzuo Y   Xie Qingmei Q  

Journal of virology 20121101 22


In 2010 and 2011, several devastating Newcastle disease (ND) outbreaks occurred in China, affecting broilers, layers, and breeders. The CK-JSX1-201005 virus was isolated from broiler breeder flocks vaccinated with the classical ND virus (NDV) vaccine program, but laying rate decreased from 80% to 30 to 40% in the clinic. Here, we report the complete genome sequence and molecular characteristic of the CK-JSX1-201005 NDV. These findings provide additional insights into the genetic variation of NDV  ...[more]

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