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Complete genome sequence of a Newcastle disease virus strain isolated from broiler breeder flocks in China.

ABSTRACT: In 2010 and 2011, several devastating Newcastle disease (ND) outbreaks occurred in China, affecting broilers, layers, and breeders. The CK-JSX1-201005 virus was isolated from broiler breeder flocks vaccinated with the classical ND virus (NDV) vaccine program, but laying rate decreased from 80% to 30 to 40% in the clinic. Here, we report the complete genome sequence and molecular characteristic of the CK-JSX1-201005 NDV. These findings provide additional insights into the genetic variation of NDV circulating in China and are useful for vaccine development for NDV.

SUBMITTER: Chen F

PROVIDER: S-EPMC3486497 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Complete genome sequence of a Newcastle disease virus strain isolated from broiler breeder flocks in China.

Chen Feng F Liu Jiajia J Liu Di D Yan Zhuanqiang Z Ji Jun J Qin Jianping J Li Haiyan H Ma Jingyun J Bi Yingzuo Y Xie Qingmei Q

Journal of virology 20121101 22

In 2010 and 2011, several devastating Newcastle disease (ND) outbreaks occurred in China, affecting broilers, layers, and breeders. The CK-JSX1-201005 virus was isolated from broiler breeder flocks vaccinated with the classical ND virus (NDV) vaccine program, but laying rate decreased from 80% to 30 to 40% in the clinic. Here, we report the complete genome sequence and molecular characteristic of the CK-JSX1-201005 NDV. These findings provide additional insights into the genetic variation of NDV ...[more]

PMID: 23087120

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