Ontology highlight
ABSTRACT:
SUBMITTER: Zhou J
PROVIDER: S-EPMC3486975 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Zhou Jiehua J Bobbin Maggie L ML Burnett John C JC Rossi John J JJ
Frontiers in genetics 20121102
Aptamers are single-stranded nucleic acids that specifically recognize and bind tightly to their cognate targets due to their stable three-dimensional structure. Nucleic acid aptamers have been developed for various applications, including diagnostics, molecular imaging, biomarker discovery, target validation, therapeutics, and drug delivery. Due to their high specificity and binding affinity, aptamers directly block or interrupt the functions of target proteins making them promising therapeutic ...[more]