Ontology highlight
ABSTRACT:
SUBMITTER: Gowin K
PROVIDER: S-EPMC3487558 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Gowin Krisstina K Thapaliya Prakash P Samuelson Jan J Harrison Claire C Radia Deepti D Andreasson Bjorn B Mascarenhas John J Rambaldi Alessandro A Barbui Tiziano T Rea Catherine J CJ Camoriano John J Gentry Amy A Kiladjian Jean-Jacques JJ O'Connell Casey C Mesa Ruben R
Haematologica 20120314 10
The Philadelphia negative myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia, and myelofibrosis, are associated with substantial vascular and transformative complications. Standard therapy for high-risk disease, particularly in patients that have failed initial therapy, remains controversial. Non-pegylated interferon has previously been shown to be effective in controlling erythrocytosis, thrombocytosis and thrombotic complications, but was found to have poor to ...[more]