Bitter taste receptor polymorphisms and human aging.
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ABSTRACT:
SUBMITTER: Campa D
PROVIDER: S-EPMC3487725 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Bitter taste receptor polymorphisms and human aging.
Campa Daniele D De Rango Francesco F Carrai Maura M Crocco Paolina P Montesanto Alberto A Canzian Federico F Rose Giuseppina G Rizzato Cosmeri C Passarino Giuseppe G Barale Roberto R
PloS one 20121102 11
Several studies have shown that genetic factors account for 25% of the variation in human life span. On the basis of published molecular, genetic and epidemiological data, we hypothesized that genetic polymorphisms of taste receptors, which modulate food preferences but are also expressed in a number of organs and regulate food absorption processing and metabolism, could modulate the aging process. Using a tagging approach, we investigated the possible associations between longevity and the comm ...[more]
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