Effect of nonadditive repulsive intermolecular interactions on the light scattering of concentrated protein-osmolyte mixtures.
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ABSTRACT:
SUBMITTER: Fernandez C
PROVIDER: S-EPMC3488766 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
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Effect of nonadditive repulsive intermolecular interactions on the light scattering of concentrated protein-osmolyte mixtures.
Fernández Cristina C Minton Allen P AP
The journal of physical chemistry. B 20101222 5
The static light scattering of three globular proteins, bovine serum albumin, ovalbumin, and ovomucoid, and binary mixtures of each protein and trimethylamine oxide (TMAO) containing between 10 and 70% protein, were measured as a function of total weight per volume concentration up to 100 g/L. The observed dependence of scattering upon concentration may be accounted for quantitatively by an effective hard sphere model incorporating an extension that takes into account the nonadditive nature of t ...[more]
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