Ontology highlight
ABSTRACT:
SUBMITTER: Chen YH
PROVIDER: S-EPMC3489787 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Chen Yi-Hsing YH Anderson Mark M Hendrickx Antoni P A AP Missiakas Dominique D
BMC microbiology 20120925
<h4>Background</h4>Staphylococcus aureus secretes EsxA and EsxB, two small polypeptides of the WXG100 family of proteins. Genetic analyses have shown that production and secretion of EsxA and EsxB require an intact ESAT-6 Secretion System (ESS), a cluster of genes that is conserved in many Firmicutes and encompasses esxA and esxB . Here, we characterize EssB, one of the proteins encoded by the ESS cluster. EssB is highly conserved in Gram-positive bacteria and belongs to the Cluster of Orthologo ...[more]