Ontology highlight
ABSTRACT:
SUBMITTER: Duncan CJ
PROVIDER: S-EPMC3495712 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Duncan Christopher J A CJ Hill Adrian V S AV Ellis Ruth D RD
Human vaccines & immunotherapeutics 20120420 6
An effective vaccine against P. falciparum malaria remains a global health priority. Blood-stage vaccines are an important component of this effort, with some indications of recent progress. However only a fraction of potential blood-stage antigens have been tested, highlighting a critical need for efficient down-selection strategies. Functional in vitro assays such as the growth/invasion inhibition assays (GIA) are widely used, but it is unclear whether GIA activity correlates with protection o ...[more]