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Bacteriophage P70: unique morphology and unrelatedness to other Listeria bacteriophages.


ABSTRACT: Listeria monocytogenes is an important food-borne pathogen, and its bacteriophages find many uses in detection and biocontrol of its host. The novel broad-host-range virulent phage P70 has a unique morphology with an elongated capsid. Its genome sequence was determined by a hybrid sequencing strategy employing Sanger and PacBio techniques. The P70 genome contains 67,170 bp and 119 open reading frames (ORFs). Our analyses suggest that P70 represents an archetype of virus unrelated to other known Listeria bacteriophages.

SUBMITTER: Schmuki MM 

PROVIDER: S-EPMC3497695 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature

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Bacteriophage P70: unique morphology and unrelatedness to other Listeria bacteriophages.

Schmuki Martina M MM   Erne Doris D   Loessner Martin J MJ   Klumpp Jochen J  

Journal of virology 20120919 23


Listeria monocytogenes is an important food-borne pathogen, and its bacteriophages find many uses in detection and biocontrol of its host. The novel broad-host-range virulent phage P70 has a unique morphology with an elongated capsid. Its genome sequence was determined by a hybrid sequencing strategy employing Sanger and PacBio techniques. The P70 genome contains 67,170 bp and 119 open reading frames (ORFs). Our analyses suggest that P70 represents an archetype of virus unrelated to other known  ...[more]

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