Ontology highlight
ABSTRACT:
SUBMITTER: Striepens N
PROVIDER: S-EPMC3497762 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Striepens Nadine N Scheele Dirk D Kendrick Keith M KM Becker Benjamin B Schäfer Lea L Schwalba Knut K Reul Jürgen J Maier Wolfgang W Hurlemann René R
Proceedings of the National Academy of Sciences of the United States of America 20121016 44
The neuropeptide oxytocin (OXT) can enhance the impact of positive social cues but may reduce that of negative ones by inhibiting amygdala activation, although it is unclear whether the latter causes blunted emotional and mnemonic responses. In two independent double-blind placebo-controlled experiments, each involving over 70 healthy male subjects, we investigated whether OXT affects modulation of startle reactivity by aversive social stimuli as well as subsequent memory for them. Intranasal OX ...[more]