Ontology highlight
ABSTRACT:
SUBMITTER: Swaminathan A
PROVIDER: S-EPMC3499482 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Swaminathan Aishwarya A Barnes Valerie L VL Fox Stephanie S Gammouh Sarah S Pile Lori A LA
PloS one 20121115 11
The role of the Sin3A transcriptional corepressor in regulating the cell cycle is established in various metazoans. Little is known, however, about the signaling pathways that trigger or are triggered by Sin3A function. To discover genes that work in similar or opposing pathways to Sin3A during development, we have performed an unbiased screen of deficiencies of the Drosophila third chromosome. Additionally, we have performed a targeted loss of function screen to identify cell cycle genes that g ...[more]