Ontology highlight
ABSTRACT:
SUBMITTER: Gorlov IP
PROVIDER: S-EPMC3499550 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Gorlov Ivan P IP Logothetis Christopher J CJ Fang Shenying S Gorlova Olga Y OY Amos Christopher C
PloS one 20121115 11
More than 400 cancer genes have been identified in the human genome. The list is not yet complete. Statistical models predicting cancer genes may help with identification of novel cancer gene candidates. We used known prostate cancer (PCa) genes (identified through KnowledgeNet) as a training set to build a binary logistic regression model identifying PCa genes. Internal and external validation of the model was conducted using a validation set (also from KnowledgeNet), permutations, and external ...[more]