Ontology highlight
ABSTRACT:
SUBMITTER: Velagapudi SP
PROVIDER: S-EPMC3500435 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
ACS chemical biology 20120914 11
There are many potential RNA drug targets in bacterial, viral, and human transcriptomes. However, there are few small molecules that modulate RNA function. This is due, in part, to a lack of fundamental understanding about RNA-ligand interactions including the types of small molecules that bind to RNA structural elements and the RNA structural elements that bind to small molecules. In an effort to better understand RNA-ligand interactions, we diversified the 2-aminobenzimidazole core (2AB) and p ...[more]