Nanoblade delivery and incorporation of quantum dot conjugates into tubulin networks in live cells.
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ABSTRACT:
SUBMITTER: Xu J
PROVIDER: S-EPMC3500567 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Publications
Nanoblade delivery and incorporation of quantum dot conjugates into tubulin networks in live cells.
Xu Jianmin J Teslaa Tara T Wu Ting-Hsiang TH Chiou Pei-Yu PY Teitell Michael A MA Weiss Shimon S
Nano letters 20121105 11
Quantum dots (QDs) have not been used to label cytoskeleton structure of live cells owing to limitations in delivery strategies, and QDs conjugation methods and issues with nonspecific binding. We conjugated tubulin to QDs and applied the emerging method of photothermal nanoblade to deliver QD-tubulin conjugates into live Hela cells. This method will open new opportunities for cytosolic targeting of QDs in live cells. ...[more]
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