Ontology highlight
ABSTRACT:
SUBMITTER: Cohen OS
PROVIDER: S-EPMC3502694 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Cohen Ori S OS Mccoy Sarah Y SY Middleton Frank A FA Bialosuknia Sean S Zhang-James Yanli Y Liu Lu L Tsuang Ming T MT Faraone Stephen V SV Glatt Stephen J SJ
Schizophrenia research 20121009 1-3
The diverse spatial and temporal expression of alternatively spliced transcript isoforms shapes neurodevelopment and plays a major role in neuronal adaptability. Although alternative splicing is extremely common in the brain, its role in mental illnesses such as schizophrenia has received little attention. To examine this relationship, postmortem brain tissue was obtained from 20 individuals with schizophrenia (SZ) and 20 neuropsychiatrically normal comparison subjects. Gray matter samples were ...[more]